Insulin-Like Growth Factor Binding Protein-3 Generation as a Measure of GH Sensitivity
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چکیده
منابع مشابه
Insulin-like growth factor binding protein 1 as a novel specific marker of hepatic insulin sensitivity.
BACKGROUND AND AIMS The liver is the main source and insulin the main regulator of IGF binding protein 1 (IGFBP-1) in humans. Here we examined how serum IGFBP-1 concentrations are related to directly measured hepatic insulin sensitivity and liver fat content in humans. METHODS We measured fasting serum (fS) IGFBP-1 concentrations and liver fat content by proton magnetic resonance spectroscopy...
متن کاملVertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3.
BACKGROUND A recent report suggested that men with vertex balding have higher levels of plasma insulin-like growth factor 1 (IGF-1). The association of its major carrier protein, insulin-like growth factor binding protein 3 (IGFBP-3), with male pattern hair loss has not been examined. OBJECTIVE We evaluated the relations of plasma concentrations of IGF-1 and IGFBP-3 with vertex balding in mid...
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the genetic polymorphism of insulin-like growth factor binding protein ( igfbp-3 ) and its association with the growth traits namely condition factor, body weight, and total length were investigated in common carp cyprinus carpio using pcr- single strand conformation polymorphism (sscp) technique. caudal fin clips from 120 c. carpio , aging 5 months, were used in this study and a 330 bp dna fra...
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Objectives The loss of muscle mass in older adults is attributed to the impaired ability of the skeletal muscle in response to anabolic stimuli and the increased activation of the proteolytic signaling pathway. With increasing age, plasma concentrations of circulating anabolic hormones and growth factors, e.g. testosterone, Insulin-like Growth Factor-1 (IGF-1) and Insulin-like Growth Factor Bin...
متن کاملInsulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.
RATIONALE Insulin-like growth factor binding protein (IGFBP)-3 modulates vascular development by regulating endothelial progenitor cell (EPC) behavior, specifically stimulating EPC cell migration. This study was undertaken to investigate the mechanism of IGFBP-3 effects on EPC function and how IGFBP-3 mediates cytoprotection following vascular injury. OBJECTIVE To examine the mechanism of IGF...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2002
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2002-020045